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About half of patients who used CAM for headache/migraine reported using it along with prescription (47.8%) or over-the-counter (OTC; 55.1%) drugs.

The odds of using CAM increased as the severity of the headache/migraine increased (severe migraine odds ratio [OR] 2.32, 95% CI: 1.41, 3.82; both recurring headache/severe migraine OR 3.36, 95% CI: 2.08, 5.43 when compared to those with recurring headaches only).

She also performed the Danish National Anthem in the company of Crown Princess Mary of Denmark.

In 2014, Nissen was a contestant on the third series of The Voice Australia.

Nissen went on to win, getting 64% of the final vote, and represented Denmark in the Eurovision Song Contest 2017.